Jul 2026
Soluplus®-based solid dispersion enhances oral bioavailability of A10: a cGAS-STING and ICD activator for bladder cancer therapy.
Evidence of the immune activation induced by A10 against BCa T24 cells is provided, and A10 could activate the cGAS-STING pathway, promote DAMPs release, and induce Immunogenic Cell Death (ICD) for anti-tumor activity against BCa cells in vitro.
Wenchao Wang, F. Dong, Junrong Lei et al.
· International journal of pha... · 0 citations