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Author

Qi Sun

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Review Sep 2026

Bone metastasis in cancer: from microenvironmental remodeling to precision therapy.

Bone metastasis remains a major determinant of disability, treatment failure, and poor survival in solid tumors. It is no longer adequately explained as a late consequence of tumor spread or as a process driven only by osteoclast-mediated bone destruction. Current evidence supports a broader view in which bone metastas...

Qin-Gan Feng, Xiu-Hai Ji, Qi Sun et al. · 0 citations
Open access Aug 2026

Single-cell transcriptomic landscape delineates pathogenic NK cell subpopulations and key mediators in systemic inflammatory response syndrome

Findings delineate dynamic NK subpopulation remodeling during SIRS and validate IGF1/IGF1R as a potential key pathway governing NK effector function, providing a transcriptomic basis for identifying candidate biomarkers and potential therapeutic targets in SIRS.

Hong-Ling Jia, Hang Zhao, Yan Li et al. · 0 citations
Review Open access Jul 2026

Diagnostic and therapeutic applications of melanoma-derived exosomes in nanomedicine

This review highlights mechanistic roles of exosomes in melanoma progression, summarizes key liquid-biopsy biomarkers, and discusses translational barriers such as standardization, scalable manufacturing, safety, and clinical validation.

Li Li, Xin Zheng, Jingrui Shi et al. · 0 citations

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