Bone metastasis remains a major determinant of disability, treatment failure, and poor survival in solid tumors. It is no longer adequately explained as a late consequence of tumor spread or as a process driven only by osteoclast-mediated bone destruction. Current evidence supports a broader view in which bone metastas...
Qin-Gan Feng, Xiu-Hai Ji, Qi Sun et al.· Seminars in Oncology· 0 citations
Findings delineate dynamic NK subpopulation remodeling during SIRS and validate IGF1/IGF1R as a potential key pathway governing NK effector function, providing a transcriptomic basis for identifying candidate biomarkers and potential therapeutic targets in SIRS.
Hong-Ling Jia, Hang Zhao, Yan Li et al.· Clinical and Experimental Me...· 0 citations
This review highlights mechanistic roles of exosomes in melanoma progression, summarizes key liquid-biopsy biomarkers, and discusses translational barriers such as standardization, scalable manufacturing, safety, and clinical validation.
Li Li, Xin Zheng, Jingrui Shi et al.· Microstructures· 0 citations
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