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Author

Qi-Qi He

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Open access Oct 2026

Lipid metabolism remodeling in human cardiomyocyte differentiation and maturation

Cardiac development involves extensive metabolic remodeling, yet dynamic changes of endogenous lipid species during human cardiomyocyte (CM) differentiation remain poorly characterized. In this study, we systematically performed high-coverage lipidomic profiling across five consecutive CM differentiation stages, using...

Hai-Te Tang, Rain Liu, Zhi-Qiang Xiong et al. · 0 citations
Aug 2026

Evolutionary characterization and pathogen-responsive expression of the Annexins in bivalves.

Annexins (ANXs) are a family of Ca2+-dependent phospholipid-binding proteins that participate in membrane dynamics and stress responses; however, their evolutionary patterns and immune functions in bivalves remain poorly understood. In this study, a total of 206 ANX genes were identified from 29 bivalve species. Their...

Hai-Xin Hu, Bei-Yu Yan, Yaoting Liu et al. · 0 citations
Sep 2026

Evolutionary diversification and Vibrio-responsive regulation of NF-κB signaling in bivalves: Evidence from Mimachlamys nobilis and comparative datasets.

The nuclear factor kappa B (NF-κB) pathway is a central regulator of innate immunity in animals, yet its evolutionary diversification in bivalve molluscs remains incompletely understood. Here, we analyzed NF-κB/Rel genes across 29 representative bivalve species from 11 families. Our analyses revealed substantial variat...

Wei-Min Liao, Bei-Yu Yan, Yi-Fan Li et al. · 0 citations

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