Chronic ultraviolet B (UVB) irradiation is a principal driver of skin photoaging, characterized by oxidative stress, mitochondrial dysfunction, fibroblast senescence, and extracellular matrix degradation. Although Camellia chekiangoleosa shows potential for anti-photoaging applications, its bioactive constituents and u...
Hong-Qi Gao, Si-Jia Feng, Jun-Qi Wang et al.· Pharmacological Research· 0 citations
Ferroptosis is a critical driver of tubular necrosis, and its effective inhibition holds significant potential for mitigating renal injury. In this study, chemical investigation of the strain Penicillium rubens MABC05 yielded nine drimane-pyrone-type meroterpenoids (1–9), including six previously undescribed analogues,...
Ling-Yan Liu, Xin-Jia Yang, Cai-Xia Hu et al.· Marine Drugs· 0 citations
It is demonstrated that Arg suppresses HCC progression in syngeneic murine models by reducing MDSC infiltration and promoting CD8+ T-cell accumulation, providing a strategy for reversing immunosuppression and potentiating immunotherapy.
Di Kang, Jun-Yuan Duan, Qi Lv et al.· Phytomedicine· 0 citations
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