Open access
Jul 2026
Genome-Wide Identification of a Chromatin-Splicing Regulatory Axis Driven by DOT1L in MLL-Rearranged Acute Myeloid Leukemia
A model in which H3K79me2 contributes to alternative splicing regulation in MLLr AML is supported, linking the core epigenetic lesion of this disease to aberrant RNA processing with potential prognostic relevance.
Qi Liu, Bowen Yang, Tianbao Li et al.
· Genes · 0 citations