Review
Open access
Sep 2026
Piezo1-mediated mechanotransduction in bone formation and fracture repair
The mechanosensitive ion channel Piezo1 is a crucial transducer of mechanical forces into biological signals governing skeletal development and fracture repair. This review summarizes its central role in bone formation, primarily through endochondral ossification. We detail how Piezo1 regulates key processes including...
Rong-Rui Wu, Yan Zhuang, Hui Yang et al.
· Biochemistry and Biophysics... · 0 citations