Open access
Aug 2026
Cholesterol Drives IFITM3 + Microglia Activation and Induces STING Mediated Neuroinflammation After Ischemic Stroke
Cerebral ischemic stroke triggers extensive neuronal membrane breakdown, releasing a massive load of cholesterol that overwhelms resident microglia. Dysregulated microglial cholesterol metabolism has been implicated in post‐stroke neuroinflammation, yet the specific pathogenic microglial subpopulations, their molecular...
Yue-lei Cheng, Yuxi Zhou, Yong-Hui Chen et al.
· CNS Neuroscience & Therapeut... · 0 citations