Context-dependent roles of resistin-like molecule β in mucosal defense and inflammatory diseases
Resistin-like molecule β (RELMβ) is a cysteine-rich secreted protein predominantly produced by intestinal goblet cells and regulated by microbial colonization, epithelial transcriptional programs, and immune signals. At the intestinal mucosal surface, recombinant murine and human RELMβ permeabilize susceptible bacteria...