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Review Sep 2026

Ubiquitination in DNA double-strand break repair: Mechanisms, regulation, and therapeutic implications.

DNA double-strand break (DSB) repair depends on tightly coordinated signaling that controls damage recognition, chromatin remodeling, pathway choice, and repair termination. Among the regulatory layers involved, ubiquitination functions as a central organizing axis of the DNA damage response (DDR), directing the ordere...

Jia-Jia Li, Hai-Feng Huang, Ming-Yuan Wang et al. · 0 citations

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