Author

Q. Cheng

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Preprint Aug 2026

OmicSync: Reliability-Aware Spatial Multi-Omics Clustering with Evidence-Constrained LLM Reasoning

OmicSync is presented, a reliability-aware spatial multi-omics framework that couples unsupervised domain clustering with evidence-constrained LLM reasoning using model-derived per-spot signals, including assignment confidence, epistemic routing uncertainty, and modality-routing weights, and OmicSync-R is introduced, which closes the reasoning-clustering loop by using automatically computed reasoning-quality scores as REINFORCE rewards.

R. Sadia, Qiang Ye, Q. Cheng · 0 citations

Open access Jul 2026

Mol-CADiff: text-conditional molecule generation via causality-aware autoregressive diffusion

Mol-CADiff is introduced, a diffusion-based framework that uses causal attention mechanisms for text-conditional molecular generation and enhances dependency modeling both within and across modalities, enabling precise control over the generation process.

Md. Atik Ahamed, Qiang Ye, Q. Cheng · Nature Communications · 0 citations