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Priyadarsini M

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Review Open access Sep 2026

Metachromatic Leukodystrophy: A Narrative Review of Pathophysiology, Diagnosis, and Therapeutic Advances

This review synthesizes current understanding of MLD's pathophysiology, including sulfatide-driven demyelination, neuroinflammation, astrogliosis, and emerging evidence of direct neuronal vulnerability from iPSC-derived models, to discuss the substantial caregiver burden associated with MLD and priorities for future re...

Priyadarsini M, S. S., S. K. et al. · 0 citations

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