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Pramod Kumar

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#protein folding Open access Sep 2026

Cytokine-induced nuclear translocation of STAT1 via a non-transferable NLS

The targeting function of nuclear localization signals (NLSs) is generally considered independent of a protein's native sequence or fold and is readily transferable to heterologous cargos. Contrary to this paradigm, rapid nuclear translocation of phosphorylated STAT1 (pSTAT1) following cytokine stimulation requires imp...

Pramod Kumar, James R. Cavey, Ruoyu Yang et al. · 0 citations

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