Supramolecular Assembly of an Antimicrobial Peptide Into a Pore.
Antimicrobial peptides (AMPs) have long been ascribed the ability to form pores. These structures, some observed, others inferred, vary in their mechanisms of action, though most are associated with lysis. Here, we show that an AMP derived from a truncated staphylococcal δ-toxin can form functional pores that do not ca...