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Poo-Reum Choi

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Aug 2026

Nicotinamide promotes lipophagy and cholesterol efflux through the SIRT1-LXRα deacetylation-ABCA1 pathway in vascular smooth muscle cells.

Atherosclerosis is characterized by the abnormal accumulation of lipids within vascular smooth muscle cells (VSMCs), which contributes to foam cell formation and plaque development. Although oxidized low-density lipoprotein (oxLDL) promotes intracellular lipid deposition, the precise mechanisms regulating cholesterol h...

Jin-Young Sung, Poo-Reum Choi, S. Kim et al. · 0 citations

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