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Open access Aug 2026

P-KNN: joint calibration of multiple pathogenicity prediction tools streamlines variant classification

Pathogenicity K-Nearest Neighbors (P-KNN) provides robust joint calibration for any set of pathogenicity prediction tools, thereby alleviating the constraint of pre-committing to a single predictor while enhancing statistical rigor and diagnostic yield.

Po-Yu Lin, N. Brandes · 0 citations

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