Piotr Roszczenko

Nanoparticles improve targeting and efficacy of endocytosis inhibitors

Endocytosis is a critical cellular process exploited by many viruses, including HIV-1 and SARS-CoV-2, for host cell entry. Inhibiting this pathway provides a promising antiviral strategy; however, existing small-molecule inhibitors often suffer from limited solubility, off-target effects, and poor bioavailability. This...