Ping Zhu

AT1R-mediated NIR-II/PA imaging-guided iCM exosome therapy for myocardial ischemia revascularization

Ischemic heart disease remains a leading cause of global mortality, primarily driven by myocardial infarction and subsequent ischemia–reperfusion injury (MI/RI) following coronary artery occlusion. This highlights a critical unmet clinical need for integrated strategies that enable both timely intervention during the a...

hnRNPK condensates facilitate enhancer–promoter looping and RNA polymerase II recruitment

Multi-omics integration reveals macrophage polarization and ferroptosis as key mechanisms underlying kaempferol’s therapeutic efficacy in peripheral artery disease

Multi-omics and experimental findings uncover macrophage polarization and ferroptosis modulation as central mechanisms mediating kaempferol’s therapeutic efficacy in PAD, providing mechanistic insights and potential molecular targets for precision intervention.

Cerium molybdate-doped polyaniline nanoplatform for GSH-depletion-enhanced chemodynamic/NIR-II photothermal synergistic therapy via ferroptosis and immune activation

Cerium molybdate-doped polyaniline nanoparticles are developed to enable a synergistic combination of photothermal therapy (PTT) and CDT, thereby triggering immunogenic cell death (ICD) and enhancing antitumor immunity and presenting a robust nanoplatform integrating chemodynamic and photothermal therapies for potent c...