Author

Ping Xu

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#protein folding Open access Sep 2026

Specific host translation perturbations promote TnSmu1 loss independently of the canonical ImmA regulator

Integrative and conjugative elements (ICEs) are major drivers of horizontal gene transfer and bacterial genome evolution. Although ICE-encoded regulatory circuits have been extensively characterized, the impact of host physiology on the stability of integrated ICEs remains poorly understood. Here, we identify a host-de...

Liang Bao, T. Kitten, Ping Xu · bioRxiv · 0 citations

Open access Aug 2026

A genome-wide in vivo screen reveals fitness pathways required for streptococcal infective endocarditis

Infective endocarditis (IE) is a life-threatening disease most often caused by blood-borne bacteria that infect previously damaged cardiac tissue. Despite the importance of this disease, the genetic basis for IE-associated fitness remains poorly defined. Here, we present the first genome-wide in vivo analysis of bacter...

Liang Bao, Jennifer Bradley, Vysakh Anandan et al. · PLoS Pathogens · 0 citations