The Critical Role of Molecular Weight in Digestion Stability and Gut Microbiota-Dependent Fermentation of Dendrobium officinale Polysaccharides.
This study systematically investigated the impact of molecular weight (Mw) on the gastrointestinal fate and gut microbiota modulation of Dendrobium officinale polysaccharides (DOP). A series of DOPs with different Mw (509-110 kDa) was obtained via ultrasonic degradation. During simulated digestion, all DOPs exhibited p...