Sep 2026
A dual-module ECAS complex couples transcription elongation and RNA processing.
These findings establish ECAS as a chromatin-associated assembly that couples productive elongation with RNA processing and establishes Aqr as a highly expressed cell that profoundly impairs leukemia initiation, maintenance, and leukemia stem cell function in MLL-rearranged leukemia.
Ying Xiang, Hong-Hong Wang, Zhi-Nang Yin et al.
· Molecules and Cells · 0 citations