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Pilar Ballesteros-Cuartero

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Open access Aug 2026

Label Noise Limits TCR-pMHC Specificity Prediction: Improved Performance Through AlphaFold3-Based Structural Modeling and Data Denoising

It is shown that combining structural modeling with label denoising substantially improves TCR-pMHC specificity prediction, making such approaches an attractive complement to current sequence-based approaches for refining TCR target selection.

Pilar Ballesteros-Cuartero, J. Lund, Morten Nielsen · 1 citation · ⚡1

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