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Author

Pietro Matricardi

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Open access Oct 2026

CD44-targeted hyaluronic acid nanohydrogels enhance macrophage uptake and preserve the anti-inflammatory efficacy of dexamethasone.

The inflammatory response is among the most critical drivers of tissue damage and systemic dysfunction. Although corticosteroids (CS) can achieve symptom remission and prevent tissue damage, systemic side effects are an issue due to the lack of targeted drug delivery. To this end, we propose a new approach to deliverin...

C. Migliorini, Meng-Yuan Cao, S. Domenichini et al. · 0 citations
Oct 2026

Investigation of the pentamidine efficacy against myotonic dystrophy type 1 exploiting polymeric- and lipid-based nanoparticles.

Myotonic dystrophy type 1 (DM1) is a genetic disorder caused by a mutation in the DMPK gene, in which an expanded CTG trinucleotide is transcribed into abnormal mRNA that accumulates in nuclear foci. These foci sequester crucial splicing factors, causing a strong mis-regulation of downstream target genes. Consequently,...

F. Carton, I. Andreana, C. Di Meo et al. · 0 citations

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