Open access
Aug 2026
Green Pomegranate Waste Extract Modulates Macrophage Immunometabolism by Suppressing the ACLY–ME1 Axis and Promotes Pro-Resolving Macrophage Functions
Background: Immunometabolic reprogramming is increasingly recognized as a fundamental driver of macrophage inflammatory activation. Although pomegranate polyphenols have been widely investigated for their anti-inflammatory activity, the underlying metabolic mechanisms remain poorly understood. Here, we investigated whe...
Paolo Convertini, Simona Todisco, M. Marsico et al.
· Biomedicines · 0 citations