Multimodal Imaging Guided Synergistically Therapy in Hypoxic Tumor based on α-NaYbF4:Tm@Cu2-xSe@ZnFe2O4-DOX Nanoplatforms Mediated by NIR Light.
The aberrant vascularization and uneven vascular distribution stemming from rapid tumor cell proliferation culminate arouse intra-tumoral hypoxia, which substantially compromises the therapeutic response to conventional chemotherapy, as well as photothermal therapy (PTT) and photodynamic therapy (PDT). In this work, we...