Open access
Oct 2026
The AP-1 clathrin adaptor has a conserved role in recycling resident proteins of the trans-Golgi network
Although the AP-1 clathrin adaptor has been studied for decades, its role in membrane trafficking has been ambiguous. Here, we systematically investigated the localization and function of mammalian AP-1. This adaptor associates with the trans-Golgi network (TGN) and with TGN-related recycling endosomes. Disruption of t...
Fernando M. Valbuena, Maddison Lessard, Adam H. Krahn et al.
· bioRxiv · 0 citations