Author

Peter Müller-Wöhrstein

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Open access Sep 2026

Scorpion toxin peptide BMK86-P1 achieves mutation-reversible inhibition of KCNA2 at the cost of reduced efficacy in heteromers and murine neurons

Solid-phase synthesized the KV1.1.2 specific scorpion toxin peptide BMK86-P1 and oxidized it with modest efficacy, highlighting the limits of peptide synthesis together with the need for testing specific compounds on complex systems.

Elisabeth M. M. Brand, Lorenz Over, Hubert Kalbacher et al. · bioRxiv · 0 citations