Development of a Multivalent Macrocyclic Peptide that Protects Against SARS-CoV-2 Infection Following Intranasal Administration
The risk of zoonotic spillover of coronaviruses poses a constant threat to humanity, as recently exemplified by SARS‑CoV-2. During the pandemic, the rapid emergence of immune escape mutations led to a loss of efficacy of both therapeutic and humoral anti‑spike antibodies, emphasizing the need for therapeutics that enga...