Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants
ABSTRACT Conformational plasticity allows class I viral fusion proteins, including the SARS‐CoV‐2 spike, to undergo major structural rearrangements that support receptor binding and membrane fusion, making them key vaccine and antiviral targets. Using high‐speed atomic force microscopy (AFM) and single‐molecule force s...