Author

Peter D. Heintzman

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Open access Oct 2026

G-ALN: a GPU-accelerated BWA-aln algorithm for palaeogenomics

Summary The most commonly used method to achieve optimal mapping for short and damaged ancient DNA (aDNA) reads is the BWA-aln algorithm with seeding disabled. However, this CPU-based algorithm is computationally demanding, as the aligner must tolerate mismatches and indels across the entire read. To improve alignment...

Bilal Sharif, Krister Hedfors, T. van der Valk et al. · bioRxiv · 1 citation

Open access Oct 2026

Ancient genomes reveal an extinct bovine species from mid-latitude Asia.

A previously undescribed bovine mitochondrial clade, termed yak X, was recently discovered in Pleistocene Asia.1 However, the genome-wide relationships of this lineage to other bovines remain unclear. Here, we present 20 Middle and Late Pleistocene yak X nuclear genomes that were recovered from Denisova Cave and other...

Jonas Oppenheimer, Alexandre Gilardet, M. Kozlikin et al. · Current Biology · 0 citations