Author

Perri Gish

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Open access Oct 2026

Profibrotic activation of fibro-adipogenic progenitors impairs myogenesis through extracellular matrix synthesis and soluble factors

The primary source of fibrosis in skeletal muscle is fibro-adipogenic progenitors (FAPs) which deposit extensive extracellular matrix (ECM). FAPs are key in supporting regeneration and myogenesis in healthy muscle but become pathogenic in fibrosis. The goal of this study was to determine the effect of fibrotic FA...

Herman Huang, Taryn Loomis, Perri Gish et al. · Skeletal Muscle · 0 citations

Open access Aug 2026

Effects of linoleic acid and its trans-10 biohydrogenation intermediates (trans-10, cis-12 conjugated linoleic acid and trans-10 18:1) on lipogenic gene expression and Δ9-desaturation indices in bovine intramuscular adipocytes

Abstract Trans-10, cis-12 conjugated linoleic acid (t10, c12-CLA) and trans-10 18:1 (t10-18:1) are major ruminal biohydrogenation intermediates of linoleic acid (LNA) under high-grain diets. T10, c12-CLA has been shown to reduce Δ9-desaturase (SCD1) activity and the cis-monounsaturated to saturated fatty acid ratio (ci...

Maykal Tsonov, Perri Gish, P. Vahmani · Journal of Animal Science · 0 citations

Open access Sep 2026

PS3-21. What’s at Steak: Effects of Linoleic Acid and Its Trans-10 Biohydrogenation Intermediates on Lipid Metabolism in Intramuscular Bovine Adipocytes.

Trans-10, cis-12 conjugated linoleic acid (t10,c12 CLA) and trans-10 18:1 (t10-18:1) are the main ruminal biohydrogenation intermediates of linoleic acid (LNA) produced under high-grain feedlot diets. T10,c12 CLA has anti-lipogenic effects, including reducing Δ9-desaturase activity in adipocytes and consequently decr...

Maykal Tsonov, Perri Gish, P. Vahmani · Journal of Animal Science · 0 citations