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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Pengwen Chen

The University of Tokyo

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Sep 2026

Programmable mRNA Nanotherapeutics through Logic Switch Design

A quantitative framework based on five key performance dimensions: dynamic range, temporal kinetics, output efficiency, spatial fidelity, and cycle retention is proposed, which discusses the emerging roles for computational modeling and artificial intelligence in enabling multiobjective optimization of these metrics an...

Pengwen Chen, Abdulaziz Alhussan, P. Cullis et al. · 0 citations
Open access Aug 2026

Disulfide-crosslinked triblock polyampholyte vesicles as a reducible platform for polyplex-based nucleic acid delivery.

Polyion complex (PIC) vesicles are attractive carriers for mRNA delivery, yet their assembly is often compromised by charged cargos that disrupt the electrostatic interactions required for vesicle formation. Here, we report triblock polyampholyte vesicles (TBPVs) that encode preferential polymer-polymer interactions, e...

Guanghao Hu, Takayoshi Watanabe, Pengwen Chen et al. · 0 citations

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