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Author

Penghui Zeng

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Open access Aug 2026

Senecavirus a 3C protease cleaves RETREG1 to antagonize ER-phagy and promote viral replication via endoplasmic reticulum calcium signaling.

Infection with Senecavirus A (SVA), an emerging picornavirus, triggers the cleavage of RETREG1, which functions as a negative regulator of viral replication, highlighting RETREG1 as a potential therapeutic target for combating SVA infection.

Jingyu Mao, Ju Yu, Penghui Zeng et al. · 0 citations
Open access Aug 2026

Y-box-binding protein 1 stabilizes the capsid protein of porcine circovirus type 2 to promote viral replication

Co-immunoprecipitation assays demonstrate that PCV2 Cap protein can maintain its own stability by binding to the cellular Y-box-binding protein 1 (YBX1) during viral infection and inhibiting the proteasomal degradation of Cap during viral infection.

Jian-Wei Zhou, Qianqian Zhang, Xue Dong et al. · 0 citations

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