Author

Peng Zheng

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#protein folding Oct 2026

Single-Molecule Studies Reveal That Water Starts to Protect Proteins Even at the ppm Level

A consensus established by extensive thermodynamic and structural studies of proteins and DNA is that water acts as an indispensable structural cofactor rather than a passive solvent for biomolecules. Nevertheless, it remains unclear whether trace water still exerts a stabilizing effect on proteins under ultradry con...

Jiu-Long Zhou, Yan Wang, Zi-Yi Wang et al. · ACS Nano · 0 citations

Oct 2026

Predictive β-Sheet Protein Stabilization via Computationally Guided Metal Coordination with Simulations and AlphaFold3.

Proteins that withstand mechanical forces in nature possess evolved architectures that resist forced unfolding, yet mimicking this robustness in engineered proteins remains challenging. Although metal coordination bonds can act as powerful molecular clamps, their incorporation has been largely empirical, with no ration...

Zhuo-Jian Lu, Sheng-Bang Xu, Bin Zheng et al. · ACS Nano · 0 citations

Open access Oct 2026

Supramolecular Elastomer Based Switchable Adhesives Regulated by Soft Confinement Induced Nano-Rod Crystals.

Supramolecular adhesives enable on-demand detachment due to their dynamic nature. However, such behavior usually at the cost of limited adhesive toughness. To promote the intrinsic compromise between adhesive toughness and switchability, we propose a soft-confinement-regulated nanorod crystallization strategy to constr...

Qi Jin, Min-Zhi Duan, Shao-Chuan Luo et al. · Advances in Materials · 0 citations