B cells in the progression from metabolic dysfunction-associated steatotic liver disease to hepatocellular carcinoma: immune regulation, microenvironmental crosstalk, and therapeutic implications.
B cells exert stage-dependent and highly heterogeneous immunoregulatory functions throughout the progression from metabolic dysfunction-associated steatotic liver disease to hepatocellular carcinoma. Their functional states are shaped by disease stage, the metabolic milieu, and tissue-specific immune niches, thereby in...