Peng Wang

In Vivo Cascade Cyclic Amplification Strategy for Detecting the Relative Expression of MYCN mRNA in Neuroblastoma.

MYCN gene copy number in neuroblastoma tissue sections is a well-established prognostic parameter used to guide clinical risk stratification. Nevertheless, the majority of neuroblastoma cases are identified at late stages, when tumors are bulky and unresectable, precluding safe tissue sampling through surgery or core b...

Tandem-Gated DNA Nanomachine Enables In Vivo Visualization of Mitochondrial Nickel Ions from Nickel Alloy Implants

No approach has been reported for the in vivo detection of mitochondrial nickel ions (Ni2+), despite their crucial importance for elucidating the early timing, dynamic progression, and potential intervention windows of nickel-induced mitochondrial damage. Therefore, a tandem-gated DNA nanomachine (C-12S-Zyme-tFNA) th...

A novel two-channel ratiometric fluorescent probe for monitoring hypochlorous acid fluctuations in inflammation.