NIR-Responsive Mitochondrial-Targeted Nanozymes With Built-In Antibacterial Function for Safe Osteoarthritis Therapy.
A mitochondrial targeted nanozyme (CuQ@SS31) is fabricated by coordinating copper with quercetin and modifying the mitochondria-homing peptide SS31 on the surface, which effectively alleviated oxidative stress, suppressed inflammation, and decelerated cartilage degradation, while demonstrating prolonged joint retention...