Domino Effect in Epimer Self-Assembly Induces Diverse Hydrogel Properties for Biomedical Applications.
Precise regulation of small-molecule self-assembly remains a formidable challenge, as subtle structural variations can trigger profound reprogramming of supramolecular architectures. Herein, we demonstrate that C18-epimerization of glycyrrhizic acid (GA) acts as a molecular switch to modulate both its self-assembly beh...