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Open access Sep 2026

4‐2 VHL‐Recruiting PROTAC Inhibits the Growth and Migration of Triple Negative Breast Cancer Cells by Triggering Pyroptosis Through Fas‐Mediated IL‐17 Signaling

SND1 is an oncoprotein found to be overexpressed in breast cancer, especially in triple‐negative breast cancer(TNBC). In our previous study, a novel SND1‐interacting peptide 4‐2 was identified, exhibiting cytotoxicity to TNBC cells by inducing SND1 degradation. This study for the first time demonstrated the degradation...

Qi-Qi Wang, Qiu-Feng Huang, Hui-Ping Ou et al. · 0 citations
Review Open access Jul 2026

Aztreonam-Avibactam against Carbapenem-Resistant Enterobacterales: Susceptibility and Genomic Analysis in a Chinese Teaching Hospital.

OBJECTIVES To investigate aztreonam-avibactam (AZA) susceptibility and molecular features of carbapenem-resistant Enterobacterales (CRE) at a Shenzhen hospital. METHODS CRE isolates were collected from Jan 2018 to Sep 2025 and analyzed by whole-genome sequencing, AZA disk diffusion, and clinical data review. Regional...

Qiaomin Zhang, Guili Zhang, Hanlian Huang et al. · 0 citations

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