To discover fungicidal candidates with potent antifungal activity, a series of novel imidazolecarboxylic acid oxime ester derivatives were designed and synthesized based on our previous research. Their antifungal activities were systematically evaluated, and the preliminary mechanism of action was investigated. Compo...
Tian-Tian Sun, Le Wang, Rui-Long Wang et al.· Journal of Agricultural and...· 0 citations
Natural products (NPs) serve as both inspirations and resources for the discovery of bioactive compounds. However, their application in green agrochemical discovery faces limitations such as low activity, short duration of efficacy, potential toxicity and residue issues from structural modifications, and constraints in...
Peng Lei, H. Yuan, Xingxing Lu et al.· Science Advances· 0 citations
A series of 37 heterocycle-substituted α-methylene-γ-butyrolactone derivatives were designed and synthesized and exhibited the strongest antioomycete activity against P. capsici and Pseudomonas syringae pv actinidiae.
Deyou Yang, Heng Li, Yong-Xin Liang et al.· Journal of Agricultural and...· 0 citations
A series of 30 novel α-methylene-γ-butyrolactone (MBL) derivatives were designed and synthesized. Bioassays revealed that several compounds exhibited potent fungicidal activities against Valsa mali, Rhizoctonia solani, and Phytophthora capsici. A25 showed the highest activity against V. mali (EC50 = 0.70 mg/L). Against...
Deyou Yang, Heng Li, Jiaying Xu et al.· Journal of Agricultural and...· 0 citations
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