Sal A protects against SILI through coordinated regulation of amino acid metabolism, redox homeostasis, apoptosis, immune responses, and inflammatory signaling pathways, and the lack of direct mechanistic validation of key molecular targets.
Peng-Hui Li, Yu-Hua He, Yi-Tao Fan et al.· Protein Peptide Letters· 0 citations
This review delves into the complex roles of circRNAs in Hippo pathway modulation and their implications for cancer progression, and aims to elucidate the mechanisms of circRNA-Hippo interactions comprehensively and translate these insights into clinical applications.
This review systematically elucidates the multidimensional regulatory mechanisms of m6A on ferroptosis regulatory factors, covering post-transcriptional modifications of the System Xc−/GSH/GPX4 antioxidant axis, iron metabolism-related proteins, and key enzymes of lipid peroxidation.
Yu-Shuo Duan, Zi-Yi Xu, Jia-Hao Liang et al.· Frontiers in Cell and Develo...· 0 citations
This study identified candidate biomarkers related to sorafenib treatment for HCC through computational analyses, experimentally validated the oncogenic function of RPS21, and predicted carbamazepine and diclofenac as potential combination therapies for precision treatment of HCC.
Mengru Zhan, Peng-Hui Li, Wan-Yi Wang et al.· Current Medicinal Chemistry· 0 citations
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