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Author

Peng-Fei Wen

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Open access Sep 2026

Primary biliary cirrhosis and inflammatory bowel disease: a two-sample bidirectional Mendelian randomization study

Observational studies have frequently reported an association between primary biliary cirrhosis (PBC) and inflammatory bowel disease (IBD). In this study, we leveraged summary-level data from genome-wide association studies (GWAS) to conduct a two-sample bidirectional Mendelian randomization (MR) analysis, with the pri...

Ming-Yi Yang, Jia-Le Xie, Jing Hu et al. · 0 citations
Review Open access Sep 2026

Mitochondrial homeostasis in musculoskeletal diseases: from pathogenic mechanisms to precision therapies.

Musculoskeletal disorders (MSDs), including osteoporosis (OP), osteoarthritis (OA), and rheumatoid arthritis (RA), represent a stubborn burden in modern medicine. They share a breakdown in mitochondrial homeostasis. Mitochondrial dysfunction serves as a central pathogenic mechanism unifying these conditions and driving...

Peng-Fei Wen, Yu-Qi Bai, Zhi Yang · 0 citations

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