Highlights What are the main findings? Subcellular inter-organelle trafficking of TBC1D15, rather than its whole-cell protein abundance, is identified as the critical switch governing mitochondria–lysosome homeostasis and mitochondrial quality control. CCCP and high-dose AuNPs modulate TBC1D15 through two divergent reg...
Peng-Fei Qiang, Yan Li, Shuang Liang et al.· Cells· 0 citations
Evidence is synthesized that CD44, through its structural domains, isoform diversity, and proteolytic processing, integrates extracellular cues to modulate key pathways to modulate key pathways such as STAT3, NF-κB, and the class III PI3K complex.
