CD58, the primary ligand of the co-stimulatory receptor CD2, plays a crucial role in the formation of the immunological synapse (IS) and the initiation of antitumor immunity involving T cells and natural killer (NK) cells. Aberrant CD58 expression, resulting from genomic inactivation, epigenetic silencing, transcript...
Peng-Fei Guo, Ming Yi, Yu-Jie Gan et al.· Molecular Cancer· 0 citations
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