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Review Open access Oct 2026

Micro/Nanostructured Materials and Microfluidic Diagnostic Platforms Enable Multimodal Detection of Circulating Tumor Cells

ABSTRACT Circulating tumor cells (CTCs), as pivotal targets in liquid biopsy, offer dynamic, multidimensional insights into tumor heterogeneity and metastatic progression. However, their extreme rarity, pronounced heterogeneity, and the complexity of the blood microenvironment severely constrain detection accuracy. Adv...

Hao Li, Jiao-Jiao Sun, Kun-Guo Liu et al. · 0 citations
Sep 2026

Trillin alleviates rheumatoid arthritis by inhibiting TXNIP-mediated mitochondrial damage and NLRP3-dependent pyroptosis.

Macrophage pyroptosis in the synovial tissue of patients with rheumatoid arthritis (RA) releases large amounts of inflammatory cytokines, which further exacerbate the pathological progression of RA. Trillin, a natural steroidal saponin in Trillium tschonoskii Maxim and other medicinal plants, exhibits potent antioxidan...

Jing-Jing He, Xin-Ying Wang, Xiao-Di Lian et al. · 0 citations

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