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Author

Peiying Li

2 papers indexed here

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Open access Sep 2026

Enhancing Treg persistence by inhibiting necroptosis restrains autoimmune pathology.

Regulatory T (Treg) cells hold great promise as next-generation therapeutics for autoimmune diseases. However, maintaining their functional persistence within inflamed tissues remains a major translational challenge. Using an in vitro system that recapitulates the inflammatory CNS milieu of multiple sclerosis (MS), tog...

Qiao-zhen Wu, Na Cui, Li Gao et al. · 0 citations
Open access Aug 2026

Cholesterol Drives IFITM3 + Microglia Activation and Induces STING Mediated Neuroinflammation After Ischemic Stroke

Cerebral ischemic stroke triggers extensive neuronal membrane breakdown, releasing a massive load of cholesterol that overwhelms resident microglia. Dysregulated microglial cholesterol metabolism has been implicated in post‐stroke neuroinflammation, yet the specific pathogenic microglial subpopulations, their molecular...

Yue-lei Cheng, Yuxi Zhou, Yong-Hui Chen et al. · 0 citations

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