Author

Peishuo Liu

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Preprint Oct 2026

QProtFuse: Query-Guided Layer Fusion for Retrieval-Augmented Protein Function Prediction

QProtFuse is proposed, which uses queries to adaptively fuse multi-layer protein features and jointly learns protein and annotation retrieval through intra-modal and cross-modal contrastive objectives and demonstrates the value of query-guided fusion and complementary training objectives for exploiting a PLM's internal...

Mian-Zhi Pan, Pei-Shuo Liu, Ya-Wen Ouyang et al. · 0 citations

Open access Jul 2026

Strict OOD Antigen-to-Antibody Retrieval with CDR-Aware Slot Late Interaction

CASLR is proposed, an antibody CDR-aware slot late-interaction retriever that encodes antigens with ESM-2, encodes antibodies with IgBert, constrains antibody-side latent slots to complementarity-determining regions (CDRs), and scores local slot compatibility instead of single-vector global similarity.

Peishuo Liu, Mianzhi Pan, Chenyang Yan et al. · bioRxiv · 0 citations