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Author

Pei-Pei Zhang

3 papers indexed here

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Review Open access Aug 2026

Efficacy and safety of antibody-drug conjugates in advanced small cell lung cancer: a systematic review and single-arm meta-analysis of prospective clinical trials

Background Antibody-drug conjugates (ADCs) are being evaluated in advanced small cell lung cancer (SCLC), but the available trials include different targets, constructs, doses, and treatment settings. We aimed to determine the overall range of reported activity and safety while clarifying whether the evidence supports...

Pei-Pei Zhang, Wei-Xin Zhao, Jia-Yu Ma et al. · 0 citations
Open access Oct 2026

A Pathological Image-Based Pathomics Signature Combined with Clinicopathological Features for Predicting Lymph Node Metastasis in Esophageal Squamous Cell Carcinoma: A Development and External Validation Study

Background: Esophageal squamous cell carcinoma (ESCC) accounts for over 80% of esophageal cancer cases globally. Lymph node status is the strongest determinant of survival after resection, yet occult disease is found in about 17% of patients classified as node-negative. We developed a postoperative model estimating the...

Kai-Ming Peng, Jie-Ming Lu, Pei-Pei Zhang et al. · 0 citations
Sep 2026

METTL1-Mediated m7G Modification of GINS2 mRNA Activates STAT3 to Drive Esophageal Squamous Cell Carcinoma Progression.

BACKGROUND METTL1-mediated m7G modification plays a procancer role in various malignant tumors, but whether it promotes the progression of esophageal squamous cell carcinoma (ESCC) by regulating the DNA replication factor GINS2 and tumor-associated macrophage polarization remains unclear. METHODS The expression and f...

Wu Han, Zhi-Min Shen, Pei-Pei Zhang · 0 citations

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