Open access
Oct 2026
FBMN-Guided Discovery of Cyanogrisides from Mutant Strain CRM005 and Structural Diversification
Through genome mining and metabolomic analysis of the mutant strain CRM005, combined with feature-based molecular networking (FBMN) deduplication, five novel natural cyanogrisides (1–5) were selectively isolated and characterized, alongside six previously reported analogs (6–11). Antiproliferative assays demonstrated...
Yu-Kang Gao, Yun Luo, Qing-Yun Wen et al.
· ACS Omega · 0 citations