Jul 2026
Fedratinib induces non-classical G2/M arrest via mitotic-kinase inhibition and synergizes with mitomycin C to suppress pancreatic ductal adenocarcinoma.
Findings highlight fedratinib as a promising repurposed therapeutic agent for PDAC and support its combination with mitomycin C as a potential new treatment strategy.
Hui-Ying Li, Pei-Ming Yang
· Molecular Cancer Therapeutic... · 0 citations