Pei Li

Novel Thiochroman‐4‐One Derivatives Bearing a Sulfonyl Hydrazone Moiety: Synthesis, Bioactivity, Molecular Simulation, and Drug‐Likeness Evaluation

Herein, a series of novel thiochroman‐4‐one derivatives bearing sulfonyl hydrazone moiety were rationally designed and synthesized via molecular hybridization strategy. The sulfonyl hydrazone pharmacophore with excellent hydrogen‐bonding interaction ability was first introduced into the thiochroman‐4‐one parent skeleto...